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GLYCOSYLATED ANTIBODIES
专利权人:
Silke Hansen
发明人:
Silke Hansen,Klaus-Peter Kuenkele,Dietmar Reusch,Ralf Schumacher
申请号:
US13298553
公开号:
US20120128664A1
申请日:
2011.11.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides an antibody comprising human IgG1 or IgG3 heavy chain constant domains that are glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is at least 99%, and in addition the amount of NGNA is 1% or less and/or the amount of N-terminal alpha 1,3 galactose is 1% or less, and uses thereof.
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