A cartridge (16), which may be suitable for use as a portion of a transdermal drug delivery apparatus (10), may include a body (96) at least partially defining an interior for containing fluid for being delivered by the transdermal drug delivery apparatus (10). The body (96) may also at least partially define first and second openings to the interior of the body (96), wherein the first and second openings are respectively proximate opposite first and second ends of the body (96). The cartridge (16) may also include a self-sealing member (108) at least partially closing the first opening, and a movable member (116) at least partially closing the second opening, wherein at least a portion of the movable member (116) is for being urged into the interior of the body (96) for increasing pressure within the interior of the body (96).
