SANDANAYAKA, Vincent P.,SHACHAM, Sharon,KAUFFMAN, Michael,SHECHTER, Sharon,McCAULEY, Dilara,LANDESMAN, Yosef,SENAPEDIS, William,SAINT-MARTIN, Jean-Richard
申请号：
AU2016213805
公开号：
AU2016213805A1
申请日:
2016.08.11
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
#$%^&*AU2016213805A120160901.pdf#####ABSTRACT OF THE INVENTION The invention generally relates to nuclear transport modulators, e.g., CRM I inhibitors, and ) more particularly to a compound represented by fonnula (I): (R )m X>；N I or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herei.m The invention also includes the synthesis and use of a compound of structural formula (I), or a phannaceutically acceptable salt or composition thereof, e.g, in the treatment, modulation and/or prevention of physiological conditions associated with CRM 1 activity.
