METHODS AND COMPOSITION FOR INHIBITING TUMOR GROWTH AND ENHANCING IMMUNE RESPONSES TO TUMORS

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专利权人:

Thomas Jefferson University;Imvax, Inc.

发明人:

David W. Andrews,Douglas C. Hooper,Arthur Howe

申请号：

US16487612

公开号：

US20200054761A1

申请日:

2018.02.22

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present disclosure provides methods and compositions for enhancing the treatment of a cancer, particularly in a human subject, by administering antibody drug conjugates (ADCs) to inhibit or kill specific myeloid/monocyte/macrophage-lineage cells. The myeloid/monocyte/macrophage-lineage cells are identified, for example, by expression of one or more of the scavenger receptors CD204 and CD163, and/or mannose receptor-1 (CD206).

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中国工程科技知识中心

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http://www.ckcest.cn/home/