COMPOSES D'HORMONE DE CROISSANCE HUMAINE RECOMBINANTS PEGYLES

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专利权人:

ASCENDIS PHARMA AS

发明人:

RAU, HARALD,KINDERMANN, SUSANNE,LESSMANN, TORBEN,RASMUSSEN, GRETHE NORSKOV,HERSEL, ULRICH,WEGGE, THOMAS,SPROGOE, KENNETT

申请号：

CA2721947

公开号：

CA2721947C

申请日:

2009.04.29

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

A chemically modified human Growth Hormone (rhGH)prepared by attaching a transient linkerwhich comprises a polyethyleneglycol. The chemically modified proteinmay have a much longer lastingrhGH activity than that of the unmodifiedrhGH, enabling reduced doseand scheduling opportunities and themodified rhGH may not cause lipoatrophy.Also includes methods of usefor the treatment and/or prevention ofdiseases or disorders in which use ofgrowth hormone is beneficial.

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