Claudiu Supuran,Shoukat Dedhar,Fabrizio Carta,Jean-Yves Winum,Paul C. McDonald
申请号：
US14078455
公开号：
US20140148400A1
申请日:
2013.11.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Derivatized coumarin-based pharmaceutical compositions and methods to use them are provided. The compositions are characterized in that they inhibit the activity of tumor-related CAIX and CAXII to a greater degree than they inhibit the activity of CAI and CAII. The compositions can be used to suppress tumor growth and/or suppress tumor metastases in a mammal.
