ROBERT KENDALL MORRISON,ZILI AN,KAREN JANE MEYRICK MORRISON,JOSH SNYDER,XIAO-CHI JIA
申请号：
PT13831502
公开号：
PT2887959T
申请日:
2013.08.23
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The invention provides an antibody-drug conjugate comprising an anti-158P1D7 antibody or antigen binding fragment thereof conjugated to monomethyl auristatin E (MMAE), wherein the antibody or fragment thereof comprises a heavy chain variable region comprising an amino acid sequence at least 80% homologous to the heavy chain variable region amino acid sequence set forth in SEQ ID NO:7 and a light chain variable region comprising an amino acid sequence at least 80% homologous to the light chain variable region amino acid sequence set forth in SEQ ID NO:8.
