The invention provides container systems, kits and methods for peritonealdialysis (PD) solutions. Such a system,for example, includes a first compartment that contains a PD osmotic agent anda second compartment that contains a PD bufferagent. The compartments maintain their respective contents separately from oneanother for purposes of transport, storage and/orsterilization. However, the compartments are fluidly couplable, so that theirrespective contents can be combined with one another,e.g., following sterilization of the agents and prior to their introductioninto the patient's abdomen. The invention provides, in otheraspects, such systems, kits and methods that provide protective structurewhich inhibits breaking of a seal prior between the secondcompartment and an outlet of the system, prior to breaking of a seal betweenthe first and second compartments.
