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ANTI-CD40 ANTIKŪNAI IR JŲ PANAUDOJIMO BŪDAI
专利权人:
Alligator Bioscience AB
发明人:
ELLMARK, Peter Bo Joakim,DAHLEN, Eva Maria
申请号:
LT12761786
公开号:
LT2753646T
申请日:
2012.09.05
申请国别(地区):
LT
年份:
2018
代理人:
摘要:
The present invention relates to antibodies (and fragments, variants, fusions and derivatives thereof) with multivalent binding specificity for CD40, which have a potency for dendritic cell activation which is higher than, or is equal to, the potency for B cell activation and wherein the antibody, antigen-binding fragment, or fusion, variant or derivative thereof has an affinity (KD) for CD40 of less than 1x10 -10 M, which have utility in the treatment of diseases such as cancer. The invention also relates to pharmaceutical compositions, uses, methods and kits comprising such antibodies.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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