Laurence A. Lasky;Susanne Baumhueter;Steven D. Rosen;Mark S. Singer
发明人:
Laurence A. Lasky,Susanne Baumhueter,Steven D. Rosen,Mark S. Singer
申请号:
US13332881
公开号:
US20120328632A1
申请日:
2011.12.21
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention relates to the inhibition of intercellular adhesion mediated by L-selectin by administering a newly identified L-selectin ligand, CD34. More particularly, the invention concerns a method for inhibiting leukocyte adhesion to endothelial cells by administering an effective amount of an isolated, purified CD34 polypeptide or an antibody capable of binding native CD34.