FORMULATION CONTAINING CYCLIN-DEPENDENT KINASE INHIBITING COMPOUND AND METHOD OF TREATING TUMORS USING THE SAME

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专利权人:

SCHERING CORPORATION

发明人:

ANTOCHSHUK, VALENTYN,BANNERJI, RAJAT,DABBARA, ANITA,PARRY, DAVID, A,SHAMEEM, MOHAMMED,STATKEVICH, PAUL,YAO, SIU-LONG

申请号：

NZ58403708

公开号：

NZ584037A

申请日:

2008.09.16

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is an IV-infusible formulation comprising the compound of Formula II: in a buffered solution having a pH of from about pH 3.4 to about pH 5, said buffered solution comprising citric acid and sodium citrate, and wherein the ratio of citric acid:sodium citrate is about 1 mole of sodium citrate to about 2.4 moles of citric acid, the formulation providing a dosage of from about 0.33 mg/m2 to about 58 mg/m2 of the compound of formula II.

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