A method of facilitating matching of a first and a second set of data related to a region of interest in a craniofacial space is disclosed. A first set of data is generated using a first, non-material penetrating, 3D data generating device, and a surface object (421) is identified in the first set of data. Further, a first coordinate (425) is identified in a first relation to the surface object (421). The second set of data is generated by using a second, material penetrating, 3D data generating device. A volume object (423) is identified in the second set of data, and a second coordinate is identified based on the volume object. The first and second coordinate have a pre-defined relationship to each other allowing for improved matching of the first set of data and the second set of data to a matched set of data.