Large and small T antigens of merkel cell polyomavirus, nucleic acid constructs and vaccines made therefrom, and methods of using same

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专利权人:

The Wistar Institute of Anatomy and Biology

发明人:

WEINER, David, B.,DUPERRET, Elizabeth

申请号：

AU2019210063

公开号：

AU2019210063A1

申请日:

2019.01.18

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

Nucleic acid molecules and compositions comprising one or more nucleotide sequences that encode a consensus Merkel Cell Polyomavirus (MCV) T antigen. Immunomodulatory methods and methods of inducing an immune response against MCV are disclosed. Method of treating infection by MCV and methods of treating or preventing Merkel Cell Carcinoma associated with MCV are disclosed. Modified consensus MCV T antigens are disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/