Provided is an information processing system capable of configuring an avatar that more realistically reflects a state of a user. The information processing system includes: vital data acquiring means for acquiring vital data including a heart rate of a user； a terminal apparatus that transmits, in real-time via a communication network, the vital data acquired by the vital data acquiring means； and an information processing server that processes the vital data transmitted from the terminal apparatus, wherein the information processing server includes: a storage unit that stores the vital data； a user state estimating unit that estimates a state of the user based on at least the heart rate and a heart rate variability calculated, based on the heart rate； an avatar data creating unit that creates display data for displaying an avatar reflecting at least an estimation result by the user state estimating unit； and a communication interface that, when a transmission request for the display data is received via the communication network, transmits the display data to a source of the transmission request.
