The present methods, systems, and kits permit the induction of multimodal injury to a subject's skin. This approach maximizes the responsiveness of the treated area to treatments for producing hair follicles； exciting, activating, and dispersing existing hair-producing structures； and bringing about other physiological changes that correspond to increased hair growth and/or the growth of more robust hairs. In contrast with conventional methodologies, the present methods and systems provide heretofore unattainable advantages through use of a multi-pronged approach of de novo hair follicle production, in combination with reorganization of existing structures to produce new follicular units, as well as pharmaceutical enhancement of both processes, and other gainful techniques.
