CHUPAK, LOUIS S.,DING, MIN,MARTIN, SCOTT W.,ZHENG, XIAOFAN,HEWAWASAM, PIYASENA,CONNOLLY, TIMOTHY P.,XU, NINGNING,YEUNG, KAP-SUN,ZHU, JULIANG,LANGLEY, DAVID R.,TENNEY, DANIEL J.,SCOLA, PAUL MICHAEL
申请号:
CA2945746
公开号:
CA2945746A1
申请日:
2015.04.10
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present disclosure generally relates to inhibitors of the PD-l/PD- Ll protein/protein and CD80/PD-L1 protein/protein interactions useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.