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TARGETING COMPOUNDS
专利权人:
The Scripps Research Institute
发明人:
Carlos F. Barbas,Christoph Rader,Subhash C. Sinha,Richard A. Lerner
申请号:
US13777680
公开号:
US20130171074A1
申请日:
2013.02.26
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides antibody targeting compounds in which the specificity of the antibody has been reprogrammed by covalently or noncovalently linking a targeting agent to the combining site of an antibody. By this approach, the covalently modified antibody takes on the binding specificity of the targeting agent. The compound may have biological activity provided by the targeting agent or by a separate biological agent. Various uses of the invention compounds are provided.
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