PROTEÍNA VI RECETORA DE COLAGÉNIO PLAQUETÁRIO RECOMBINANTE, ANTICORPOS E SEUS USOS

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专利权人:

SANOFI-AVENTIS DEUTSCHLAND GMBH

发明人:

KENNETH J. CLEMENTSON

申请号：

PT11001216

公开号：

PT2341141E

申请日:

2000.04.25

申请国别(地区):

PT

年份:

2015

代理人:

摘要：

The invention relates to Glycoprotein VI (GPVI), its isolation, purification, and methods for recombinant production. Especially, the invention relates to the use of GPVI, preferably recombinant GPVI, in the treatment of disorders and pathological events correlated directly or indirectly to blood coagulation disorders such as thrombotic and cardiovascular diseases.The extracellular recombinant protein can also be used for establishing screening assays to find potential inhibitors of the membrane bound GPVI in order to inhibit binding of thrombocytes and platelets, respectively, to collagen.

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