APGAR, JAMES REASONER,MADER, MICHELLE MARIE,PARRIS, KEVIN DELOS
申请号:
SG11201408042Y
公开号:
SG11201408042YA
申请日:
2013.06.12
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.