YEH VINCE,LI XIAOLIN,LIU XIAODONG,LOREN JON,MOLTENI VALENTINA,NABAKKA JULIET,NGUYEN BAO,PETRASSI HANK MICHAEL JAMES
申请号:
TN2014000061
公开号:
TN2014000061A1
申请日:
2014.02.10
申请国别(地区):
TN
年份:
2015
代理人:
摘要:
The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRa, PDGFRss) kinases.