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Alcohol-resistant formulations
专利权人:
CIMA LABS INC.
发明人:
HAMED EHAB
申请号:
NZ60353111
公开号:
NZ603531A
申请日:
2011.05.09
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier and coated granules containing a high water-soluble, high dose drug. The dosage form has alcohol resistance and may also have crush resistance. Specifically disclosed viscosity modifiers include gelling polymers such as: sodium alginate, hydroxypropylmethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, sodium carboxymethylcellulose, methylcellulose, crosslinked polyacrylic acid (e.g., carbomers), gelatin, pectins, gums (e.g., gum arabic, gum tragacanth, xanthan gums, and guar gums), polyethylene oxides, Konjac flour, carrageenan, or mixtures thereof
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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