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FORMULATION PHARMACEUTIQUE ORALE SOUS FORME DE SUSPENSION AQUEUSE DE MICROCAPSULES PERMETTANT LA LIBERATION MODIFIEE DE PRINCIPE(S) ACTIF(S)
专利权人:
FLAMEL TECHNOLOGIES
发明人:
CASTAN, CATHERINE,GUIMBERTEAU, FLORENCE,MEYRUEIX, REMI
申请号:
EP03745832.0
公开号:
EP1492511B3
申请日:
2003.04.07
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention concerns liquid pharmaceutical formulations, for oral delivery, with modified release of active principle(s) excluding amoxicillin and consisting of suspensions of coated particles of active principles (microcapsules). The microcapsules constituting the dispersed phase of the suspension are designed, according to the invention, to enable modified release of the active principle(s), in accordance with a profile which remains unaltered during the shelf life of the liquid suspension. Therefor, the invention consists in selecting a coating composition specific to the microcapsules consisting of at least four components enabling preservation of said microcapsules in water without altering their properties of modified release of the active principle, said liquid phase being furthermore saturated with active principle(s).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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