Jaroskova, Libuse,Linders, Joannes Theodorus Maria,Buyck, Francis Robert Nestor,Veken, Louis Jozef Elisabeth Van der
申请号：
NO20065615
公开号：
NO338504B1
申请日:
2006.12.06
申请国别(地区):
NO
年份:
2016
代理人:
摘要：
the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is 1 or 2 M represents a direct bond or a C1-3alkyl linker optionally substituted with one or two substituents selected from C1-4alkyl, C1-3alkyloxy-C1-4alkyl-, hydroxy-C1-4alkyl-, hydroxy, C1-3alkyloxy- or phenyl-C1-4alkyl- R1 and R2 each independently represent hydrogen, halo, cyano, hydroxy, C1-4alkyl optionally substituted with halo, C1-4alkyloxy-optionally substituted with one or where possible two or three substituents selected from hydroxy, Ar1 and halo R3 represents hydrogen, halo, C1-4alkyl, C1-4alkyloxy-, cyano or hydroxy R4 represents hydrogen, halo, C1-4alkyl, hydroxy, cyano or C1-4alkyloxy-optionally substituted with one or where possible two or three substituents selected from hydroxy and halo R5 represents hydrogen, C1-4alkyl or Ar2&mdashC1-4alkyl- R6 represents hydrogen, hydroxy, halo, C1-4alkyl or C1-4alkyoxy- R7 represents hydrogen or R7 and R5 taken together with the carbon atom to which they are attached from a &mdashC2-alkyl-linker Ar1 and Ar2 each independently represent phenyl or naphtyl wherein said phenyl and naphtyl are optionally substituted with C1-4alkyl, C1-4alkyloxy-, or phenyl-C1-4alkyl.
