Methods and compositions for altering photophysical properties of fluorophores via proximal quenching

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专利权人:

Cornell University

发明人:

Scott Blanchard,Roger Altman,J. David Warren

申请号：

US14591090

公开号：

US09849196B2

申请日:

2015.01.07

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention is directed to fluorophore-containing compositions and configurations wherein proximity between the fluorophore and one or more protective agents (PAs) modifies the lifetime of fluorescent and/or dark states, their frequency of occurrence, and the total lifetime of fluorescence in order to appropriately modify the photophysical characteristics of the fluorophore. The invention is also directed to methods that utilize these compositions and configurations.

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