HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS

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专利权人:

发明人:

申请号：

HK11109538.7

公开号：

HK1155439A

申请日:

2011.09.09

申请国别(地区):

HK

年份:

2012

代理人:

摘要：

Hydrazino, oxyamino and carbonyl-based monomers and methods for incorporation into oligonucleotides during enzymatic synthesis are provided. Modified oligonucleotides are provided that incorporate the monomers provided herein. Immobilized oligonucleotides and oligonucleotide conjugates that contain covalent hydrazone or oxime linkages are provided. Methods for preparation of surface bound oligonucleotides are provided. Methods for the preparation of oligonucleotide conjugates are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/