The present invention relates to a polypeptide comprising a macadamia protein selected from the group comprising a protein running in a 2D SDS PAGE at pH 6.3 to 8.7 and 53 to 67 kDa and a protein running in a 2D SDS PAGE at pH 6.5 to 7.9 and 20 to 25 kDa or an antigenic variant thereof, preferably the protein running at pH 6.3 to 8.7 and 53 to 67 kDa or an antigenic variant thereof.