Yong Zu Kim,Tae Kyo Park,Sung Ho Woo,Hyang Sook Lee,Sun Young Kim,Jong Un Cho,Doo Hwan Jung,Youngun Kim,Hyun Jin Kwon,Kyu Man Oh,Yunseo Chung,Yun Hee Park
申请号：
US15054257
公开号：
US20160213786A1
申请日:
2016.02.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention provides methods for preparing an antibody-active agent conjugate. The conjugate comprises an antibody, a cysteine residue of an amino acid motif that can be recognized by an isoprenoid transferase located at or after the carboxy-terminus of the antibody, an isoprenoid unit operably linked to the cysteine residue, and an active agen. The invention also provides a composition comprising the antibody-active agent conjugate prepared by the methods.
