Compounds are provided that are modulators of the CCR2 receptor. The compounds have the general formula (I): and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activtation of CCR2 receptors.本發明提供作為CCR2受體之調節劑的化合物。該等化合物具有通式(I):且適用於用來治療涉及CCR2受體之病理性活化之疾病及病症的醫藥組合物、方法中。