Cho, Jae-Pyoung,Lee, Pung-Sok,Lee, Seul-A,Jeong, Min-Ho,Lee, Mase
申请号：
AU2013264518
公开号：
AU2013264518B2
申请日:
2013.05.21
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The present invention provides a multilayer coating form (multilayer-coated form) of pharmaceutical composition comprising an omega-3 fatty acid or an alkyl ester thereof and a statin based drug. More specifically, the present invention provides an orally administered pharmaceutical composition comprising: (a) a gelatin capsule core containing an omega-3 fatty acid or an alkyl ester thereof； (b) a first coating layer formed by coating, onto the gelatin capsule core, hydroxypropyl methylcellulose and a copolymer comprising a 1:2:1 weight ratio of butyl methacrylate and (2-dimethylaminoethyl) methacrylate and methyl methacrylate； and (c) a second coating layer formed by coating, onto the first coating layer, a coating solution containing a statin based drug.
