KLINGUER HAMOUR CHRISTINE,JOUHANNEAUD ALEXANDRA,GRENIER CAUSSANEL Véronique,BERGER SVEN
申请号：
IN9233/DELNP/2012
公开号：
IN2012DN09233A
申请日:
2012.10.25
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The present invention relates to a novel isolated humanized antibody or the derived compounds or functional fragments of same capable of binding to CXCR4 but also of inducing conformational changed of the CXCR4 homodimers and/or heterodimers. More particularly the present invention relates to hz515H7 antibodies specific to the CXCR4 protein as well as their use for the treatment of cancer. Pharmaceutical compositions composed of such antibodies and a process for the selection of such antibodies are also covered.
