The present invention provides a system and a method for tissue characterization based on Optical Coherence Tomography (OCT) imaging. The system comprising: an imaging unit for optical OCT imaging to provide an image of tissue sample, a computing unit connected to the imaging unit for receiving the image of tissue sample for characterizing the tissues, a storage unit for storing the data received from the computing unit, a display unit for displaying output from the computing unit, a network unit for transmitting the output received from the computing unit and interacting with other unit(s) of the system therefore the computing unit facilitate tissue specific imaging and reducing visual cluttering due to photon scattering by unspecific tissue.
