This invention is a plastic device to hold glass ampoules, vials and other containers, designed to prevent sharp injuries when loading them, for use by health workers, in anywhere where they use glass ampoules, in accordance with international biosafety standards. This holder consists of a plastic structure of three parts. The rear part is flat. The base has plastic tabs that help ensure the stability of the ampoules. The top has holes designed to facilitate placement of the ampoules, with a slightly higher diameter than that ampoules will accommodate. This device should be used as follows: Place the ampoule in the corresponding hole, open the ampoules using openers available, load the syringe, rotate 180 degrees the holder on the sharps container so that the ampoule fall by self-gravity, avoiding any contact between the healthcare worker with the broken ampoule, eliminating the possibility of injury.