Method for inducing cross-reactive immune responses to the human immunodeficiency virus (HIV) in a host by administering feline immunodeficiency virus (FIV) capsid (CA) or reverse transcriptase (RT) immunogens
Janet K. Yamamoto,Jennifer White Janelle,Barbara Aurea Torres,Maki Arai,Taishi Tanabe,Ruiyu Pu
申请号：
US12407730
公开号：
US08182820B2
申请日:
2009.03.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The subject invention pertains to materials and methods for detecting, preventing and treating retroviral infections in humans and other animals susceptible to infection by retrovirus. It has been discovered that FIV can be transmitted from cats to humans and that the FIV can infect human cells in vivo and that antibodies generated by the infected person cross-react with HIV antigens. Thus, the methods and compositions of the subject invention can be used to detect, prevent and treat FIV infection in humans and other non-feline animals that are susceptible to FIV infection. The methods and compositions of the invention can also be used to prevent and treat infection by HIV in humans.
