Polynucleotide agents targeting patatin-like phospholipase domain containing 3 (PNPLA3) and methods of use thereof

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专利权人:

Alnylam Pharmaceuticals; Inc.

发明人:

Gregory Hinkle

申请号：

US15917990

公开号：

US10597661B2

申请日:

2018.03.12

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention relates to polynucleotide agents targeting a Patatin-Like Phospholipase Domain Containing 3 (PNPLA3) gene, and methods of using such polynucleotide agents to inhibit expression of a PNPLA3 gene and methods of treating subjects having Nonalcoholic Fatty Liver Disease (NAFLD) and/or a PNPLA3-associated disorder.

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