ANAND, RAJAN,亚安德 莱杰,亞安德 萊傑,APGAR, JAMES M.,艾波卡 詹姆士M,艾波卡 詹姆士M,BIFTU, TESFAYE,比夫杜 泰斯菲,比夫杜 泰斯菲,CHEN, PING,陈平,陳平,CHU, LIN,朱麟,朱麟,COLANDREA, VINCENT J.,寇兰卓亚 文森J,寇蘭卓亞 文森J,DONG, GUIZHEN,董贵岑,董貴岑,DROPINSKI, JAM
申请号：
TW101124999
公开号：
TWI449702B
申请日:
2012.07.11
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.新穎的結構式(I)化合物為AMP蛋白激酶之活化劑且適用於治療、預防及抑制由AMPK活化之蛋白激酶介導之疾病。本發明化合物適用於治療2型糖尿病、高血糖症、代謝症候群、肥胖症、高膽固醇血症及高血壓。
