Crystalline forms of an alkoxyimidazol-1-ylmethyl biphenyl carboxylic acid

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专利权人:

THERAVANCE BIOPHARMA R&D IP LLC

发明人:

FATHEREE PAUL R.,THALLADI VENKAT R.

申请号：

NZ60980411

公开号：

NZ609804A

申请日:

2011.11.09

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

The disclosure relates to crystalline salt forms, namely the hemi-edisylate and hemi-napadisylate forms of 4&rsquo-{ 2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl} -3&rsquo-fluorobiphenyl-2-carboxylic acid. The disclosure also relates to pharmaceutical compositions comprising these crystalline forms, methods for forming them and methods of using the crystalline forms in medicaments for the treatment of diseases such as heart disease or hypertension.

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