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成人T細胞白血病/リンパ腫の発症抑制剤の有効成分をスクリーニングする方法
专利权人:
国立大学法人;大分大学
发明人:
伊波 英克,緒方 正男,長谷川 秀樹
申请号:
JP2008087280
公开号:
JP5292608B2
申请日:
2008.03.28
申请国别(地区):
JP
年份:
2013
代理人:
摘要:

PROBLEM TO BE SOLVED: To provide a method for screening a sideration inhibitor of adult T cell leukemia/lymphoma (ATLL) having an effect for delaying or preventing the sideration of ALTT by clearing the sideration mechanism of ATLL and using the inhibition of the sideration mechanism of ATLL, and the sideration inhibitor of ATLL based on the sideration mechanism of ATLL.

SOLUTION: The screening method can be executed by using the bonding inhibition of Tax and the CBD region of Cdc37 as an index. The sideration inhibitor of ATLL contains a substance, which has action for inhibiting the bonding of Tax and the CBD region of CDc37, as an effective component.

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