Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patients heart, and create a three-dimensional model representing at least a portion of the patients heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patients heart and determine a fractional flow reserve within the patients heart based on the three-dimensional model and the physics-based model.