Sergei Gryaznov,Megan Fitzgerald,Antitsa Dimitrova Stoycheva,Jin Hong
申请号：
US15810857
公开号：
US20180179542A1
申请日:
2017.11.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure provides oligonucleotide compositions that target the covalently closed circular (ccc) DNA of hepatitis B virus (HBV). Also disclosed herein are methods for treating a subject diagnosed with, or suspected of having an HBV infection and/or an HBV-associated disorder, e.g., chronic hepatitis B infection, liver failure or cirrhosis and hepatocellular carcinoma.
