Medical device delivery systems having internal cannulated joints are provided. Aninternal compression member has a distal mating end portion, an inner guide channelmember has first and second end portions defining a channel. An insert body proximalconnecting end portion having an exit port operatively couples the compressionmember mating end portion and insert body distal mating end portion operativelycouples the inner member second end portion, the insert body connecting and matingend portions defining a lumen. Alternatively, the insert mating end portionis implanted into the inner member second end portion. Alternatively, the insertmating end portion disposes about the inner member second end portion, and a tubularouter sleeve has a proximal mounting end portion disposed about the insert matingend portion, whereby at least one junction operatively couples the inner membersecond end portion, insert mating end, and outer sleeve mounting end portion.