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SUBSTITUTED PYRAZOLOPYRIMIDINES AS GLUCOCEREBROSIDASE ACTIVATORS
专利权人:
as Represented by by the Secretary;The United States of America; Dept of Health and Human Service
发明人:
Juan Jose Marugan,Noel Southall,Ehud Goldin,Wei Zheng,Samarjit Patnaik,Ellen Sidransky,Omid Motabar,Wendy Westbroek
申请号:
US15141275
公开号:
US20160346284A1
申请日:
2016.04.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Substituted pyrazolopyrimidines and dihydropyrazolopyrimidines and related compounds, their methods of manufacture, compositions containing these compounds, and methods of use of these compounds in treating lysosomal storage disorders such as Gaucher disease are described herein. The compounds are of general Formula (I)in which variables R1-R7 and X are described in the application.
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