Synthesis of carbamoylpyridone HIV integrase inhibitors and intermediates

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专利权人:

发明人:

Takashi Kawasuji,Daiki Nagamatsu

申请号：

US14272823

公开号：

US09242986B2

申请日:

2014.05.08

申请国别(地区):

US

年份:

2016

代理人:

摘要：

A synthesis approach providing an early ring attachment via a bromination to compound 1-1 yielding compound II-II, whereby a final product such as AA can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q.

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中国工程科技知识中心

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