Eduardo Induni;David Paniagua;R. David Fish;Francisco Lopez-Jimenez;Carlos Mejia
发明人:
David Paniagua,Eduardo Induni,Carlos Mejia,Francisco Lopez-Jimenez,R. David Fish
申请号：
US10887688
公开号：
US08308797B2
申请日:
2004.07.10
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention comprises a percutaneously implantable replacement heart valve device and a method of making same. The replacement heart valve device comprises a stent member made of stainless steel or self-expanding nitinol, a biological tissue artificial valve means disposed within the inner space of the stent member. An implantation and delivery system having a central part which consists of a flexible hollow tube catheter that allows a metallic wire guide to be advanced inside it. The endovascular stented-valve is a glutaraldehyde fixed bovine pericardium which has two or three cusps that open distally to permit unidirectional blood flow. The present invention also comprises a novel method of making a replacement heart valve by taking a rectangular fragment of bovine pericardium treating, drying, folding and rehydrating it in such a way that forms a two- or three-leaflet/cusp valve with the leaflets/cusps formed by folding, thereby eliminating the extent of suturing required, providing improved durability and function.
