William H. Frey, II,Richard M. Bergenstal,Leah R. Bresin Hanson,Anders L. Carlson
申请号:
US15861853
公开号:
US20180193576A1
申请日:
2018.01.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present system is directed in one embodiment to a method of administration of a therapeutic composition for treatment, prevention and/or mitigation of the frequency and/or severity of impaired awareness of hypoglycemia (IAH). The method includes administering one or more therapeutic agent(s) or composition(s) comprising insulin to the upper third of a patient's nasal cavity, thereby delivering the therapeutic composition directly to the patient's central nervous system for treatment, prevention and/or mitigation of the frequency and/or severity of IAH. In still another embodiment, the therapeutic composition comprises a non-zinc containing form of insulin.