The disclosure relates to methods, treatment regimens, uses, kits and therapies for treating asthma, such as severe asthma, by employing IL-17 antagonists to a patient population defined by serum concentration of IgE and optionally also an eosinophil count in peripheral blood.本發明係關於藉由將IL-17拮抗劑施用給患者群體以用於治療氣喘(諸如重度氣喘)之方法、治療方案、用途、套組及療法,該患者群體係藉由IgE血清濃度及亦視情況末梢血液中嗜酸性白血球之計數界定。