The present invention relates to contain [2-(6-amino-purine-9-yl)-1-methyl-ethoxyl methyl]-phosphonic acids diisopropoxy ketonic oxygen ylmethyl ester (Viread, Viread ) and (2R, 5S, cis)-4-amino-5-fluoro-1-(2-methylol-1,3-oxathiolane-5-yl)-(1H)-pyrimid-2-one (emtricitabine, Emtriva TM, (-)-cis FTC) and the treatment combination of physiologic function derivant.Described combination can be used for treating HIV to be infected, and comprises that nucleoside and/or non-nucleosidic inhibitors are had chemical sproof HIV mutant infection.The invention still further relates to the pharmaceutical composition and the preparation of the combination that contains described Viread and emtricitabine and physiologic function derivant thereof, and the Therapeutic Method that uses this based composition and preparation.
