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Heteroaryloxy quinazoline derivative
专利权人:
Masanori Asai;Akio Ohno;Norikazu Otake;Takuya Suga;Tomoharu Iino
发明人:
Tomoharu Iino,Akio Ohno,Norikazu Otake,Takuya Suga,Masanori Asai
申请号:
US12742113
公开号:
US08232284B2
申请日:
2008.11.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are compounds of the following formula and their pharmaceutically-acceptable salts, which have an effect of glucokinase activation and are useful in the field of medicines for treatment for diabetes, obesity, etc.(wherein ring A represents a pyrazolyl group optionally having a lower alkyl group, etc.; ring B represents a heteroaryl group; R represents a lower alkyl group, etc.; R1 represents a group of a formula:(wherein R11 and R12 each independently represent a hydrogen atom, etc.; m indicates an integer of from 2 to 6), etc.;R2 represents a lower alkyl group, etc.; r indicates an integer of from 0 to 3; k indicates an integer of from 0 to 4).
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