Oscar MAMMOLITI,Koen Karel JANSEN,Adeline Marie Elise PALISSE,Caroline Martine Andrée Marie JOANNESSE,Christel Jeanne Marie MENET,Brigitte ALLART,Sandy EL BKASSINY
申请号：
US16081797
公开号：
US20190388421A1
申请日:
2017.02.23
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention discloses compounds according to Formula I:Wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6a, X, Cy1, Cy2, and the subscript n and m are as defined herein. The present invention relates to antagonists compounds of sphingosine 1-phosphate (S1P) receptor, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, inflammatory diseases, autoimmune diseases, metabolic diseases, cardiovascular diseases, and/or proliferative diseases by administering the compound of the invention.
