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CELL-BASED NEOANTIGEN VACCINES AND USES THEREOF
专利权人:
Fred Hutchinson Cancer Research Center
发明人:
Stanley R. RIDDELL,Joshua VEATCH
申请号:
US16098808
公开号:
US20190224236A1
申请日:
2017.05.04
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to immune cells that express an exogenous neoantigen and an immunogenicity enhancer, or to T cells that express an exogenous neoantigen, and their use in treating a disease or disorder, such as cancer for tumor associated neoantigens. Related expression constructs, kits, host cells, pharmaceutical compositions, and methods are also provided.
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