DIANNA M. MURPHY JORDAN,ARUN V. IYER,AXEL NEUBAUER,CHRISTINE MARGARET MUEHLENTHALER,BRIAN THOMAS MARTINSON
申请号：
ARP130105051
公开号：
AR094296A1
申请日:
2013.12.27
申请国别(地区):
AR
年份:
2015
代理人:
摘要：
An immunogenic composition comprising: a) one or more antigens of M. hyorhinis and one or more antigens of M. hyosynoviae； and (b) a Carrier acceptable from the standpoint of pharmacist. In addition, an immunogenic composition comprising a) one or more antigens of mycoplasma Mycoplasma bacteria selected from the group consisting hyorhinis, M. and M. M. hyopneumoniae.Hyosynoviae； and b) one or more components of a system of eukaryotic cells. In addition, an immunogenic composition obtained by a method comprising a) cultivate Mycoplasma bacteria selected from the group consisting hyorhinis, M. and M. M. hyopneumoniae.Hyosynoviae in a system of eukaryotic cells with a reduced amount of Serum； (b) to obtain an Antigen of mycoplasma bacteria； and (c) add a Carrier acceptable from the standpoint of pharmacist.Claim: a method for immunizing a subject, characterized in that it comprises administering to the subject an immunogenic composition according to any one of claims 1 to 38.Claim 42: The Method according to claim 18, wherein the method generates an improvement in efficacy parameter selected from the group consisting of a shorter duration of bacteremia or bacterial load, a Lower D combinations And both, compared with a subject from a nonimmunized control Group of the same species.Una composición inmunogénica que comprende: a) uno o más antígenos de M. hyorhinis y uno o más antígenos de M. hyosynoviae； y b) un portador aceptable desde el punto de vista farmacéutico. Además, una composición inmunogénica que comprende a) uno o más antígenos de Mycoplasma de bacterias de Mycoplasma seleccionadas del grupo que consiste en M. hyorhinis, M. hyopneumoniae y M. hyosynoviae； y b) uno o más componentes de un sistema de células eucarióticas. Además, una composición inmunogénica obtenida mediante un método que comprende a) cultivar bacterias de Mycoplasma seleccionadas del grupo que consiste en M. hyorhinis, M. hyopneumoniae y M. hyosynoviae en un sistema de células eucarióticas co
